I’ve got a recipe that’s about to become your new weeknight hero: Pepperoni Pizza Mac and Cheese. It’s what happens when two comfort food favorites collide in one glorious, cheesy dish. Think creamy mac and cheese, but with that unmistakable pizza flavor from pepperoni, mozzarella, and Italian seasonings. Ready in under 30 minutes, it’s perfect for those evenings when you want something satisfying without the fuss. The kids will devour it, but trust me, you’ll be sneaking seconds too. Want to know the secret to making it irresistible?
Why You’ll Love this Pepperoni Pizza Mac and Cheese
If you’re tired of the same old mac and cheese recipe, this pepperoni pizza version will absolutely rock your world. I mean, who doesn’t love the combo of gooey cheese and spicy pepperoni? It’s like your two favorite comfort foods had a delicious baby.
What makes this dish special is how it transforms ordinary mac and cheese into something extraordinary with just a few pizza-inspired add-ins. The Italian seasoning and pepperoni bring that classic pizza flavor, while three different cheeses create the ultimate creamy texture.
Perfect for picky eaters, too—kids go crazy for this stuff. And the best part? It’s ready in under 30 minutes, making it ideal for busy weeknights when I’m craving something satisfying but don’t have hours to cook.
What Ingredients are in Pepperoni Pizza Mac and Cheese?
To make this incredible fusion dish, you’ll need a handful of simple ingredients that combine the best of both pizza and mac and cheese worlds.
- 8 ounces elbow macaroni
- 2 cups shredded mozzarella cheese
- 1 cup shredded cheddar cheese
- 2 cups milk
- 2 tablespoons butter
- 2 tablespoons all-purpose flour
- 1/2 cup pepperoni, chopped
- 1/2 teaspoon Italian seasoning
- 1/4 cup Parmesan cheese
Feel free to customize this recipe by adding optional ingredients like diced tomatoes or fresh basil at the end for an even more authentic pizza flavor—these little tweaks can really take the dish from good to mind-blowing.
How to Make this Pepperoni Pizza Mac and Cheese
Step 1: Cook the Pasta
Cook 8 ounces of elbow macaroni according to the package directions until al dente.
Remember, nobody likes mushy pasta—we want it to hold up nicely against our rich cheese sauce.
Step 2: Make the Roux
Melt 2 tablespoons of butter in a large saucepan over medium heat.
Once melted, whisk in 2 tablespoons of flour to create a smooth paste, cooking for about 1 minute until it smells slightly nutty.
Step 3: Create the Cheese Sauce Base
Gradually pour in 2 cups of milk while continuously whisking to prevent lumps.
Bring the mixture to a gentle simmer, stirring frequently until it thickens enough to coat the back of a spoon—this magic moment usually takes 3-5 minutes.
Step 4: Add the Cheeses
Remove the sauce from heat and stir in 2 cups of shredded mozzarella and 1 cup of shredded cheddar cheese until completely melted and velvety smooth.
Can we just take a moment to appreciate the glory of melted cheese?
Step 5: Combine Everything
Add the cooked and drained macaroni to your cheese sauce, folding gently to coat every nook and cranny.
Then mix in 1/2 cup of chopped pepperoni and 1/2 teaspoon of Italian seasoning, distributing all that pizza-y goodness throughout.
Using a premium food processor would make chopping pepperoni and grating cheeses much faster and more uniform for this recipe.
Step 6: Prepare for Baking
Transfer this magnificent mixture to a greased baking dish, spreading it out evenly.
Sprinkle 1/4 cup of Parmesan cheese over the top for that perfect crispy, golden finish we’re all dreaming about.
Step 7: Bake to Bubbly Perfection
Bake at 375°F for about 20 minutes, or until the edges are bubbly and the top has developed a gorgeous golden crust.
The anticipation might kill me, but I promise the wait is worth it.
Step 8: Add Optional Pizza Toppings
For an extra punch of pizza authenticity, consider adding some diced fresh tomatoes and torn basil leaves right before serving.
These fresh elements brighten up the rich, creamy base and really drive home that pizza inspiration.
What to Serve with Pepperoni Pizza Mac and Cheese
This gloriously indulgent comfort food mashup deserves some thoughtful sidekicks for a complete dinner.
A simple green salad with vinaigrette cuts through all that creamy richness—think arugula with lemon dressing for a peppery contrast.
Garlic bread might seem like carb overload, but honestly, when has that ever stopped anyone?
For vegetables that stand up to the bold flavors, try roasted broccoli with a sprinkle of red pepper flakes.
On the beverage front, a cold craft root beer works surprisingly well, or go with a medium-bodied red wine if you’re feeling grown-up.
And for the kids (or kids at heart), some crispy breadsticks for dipping into any extra cheese sauce that might be lingering in the corners of your plate.
Pepperoni Pizza Mac and Cheese Substitutions and Variations
• Pasta Options: Swap elbow macaroni for rotini, shells, or gluten-free pasta.
Chickpea or lentil pasta adds protein.
• Cheese Swaps: No mozzarella? Try provolone or fontina.
For dairy-free needs, use plant-based cheese alternatives and non-dairy milk.
• Meat Variations: Replace pepperoni with cooked Italian sausage, bacon, or ham.
Vegetarians can use plant-based pepperoni or add mushrooms.
- Pizza-Inspired Add-Ins: Fold in sautéed bell peppers, black olives, or caramelized onions for supreme pizza vibes.
- Spice It Up: Add red pepper flakes, a dash of hot sauce, or sliced jalapeños for heat lovers.
- Breadcrumb Topping: Mix panko with a little olive oil and Italian herbs for a crispy crust.
- Fresh Finish: A sprinkle of fresh basil or oregano right before serving brightens everything up.
Who doesn’t love that pop of green?
Leftovers and Storage for this Pepperoni Pizza Mac and Cheese
This mac and cheese actually tastes even better the next day, once all those pizza flavors have had time to get cozy with each other.
To store leftovers:
- Refrigerate in an airtight container for up to 4 days. The cheese will solidify a bit, but don’t worry!
- For freezing, portion into individual containers and freeze for up to 3 months. Future-you will thank present-you for this preparation.
When reheating, add a splash of milk (about 1-2 tablespoons per cup) to bring back that creamy texture.
Microwave on medium power, stirring halfway through, or warm in a covered dish in a 325°F oven until bubbly again.
To prevent the dreaded dryness, cover the dish when reheating.
And those crispy edges that form when reheated? Those are little flavor treasures that might make leftovers even more crave-worthy than the original!
Final Thoughts
This Pepperoni Pizza Mac and Cheese beautifully marries two beloved classics into one irresistible dish.
The creamy cheese sauce, punctuated with savory pepperoni and Italian seasonings, creates something that’s more than the sum of its parts. It’s the perfect weeknight solution when you’re torn between pizza night and something homemade, or when you need to please both the mac and cheese lovers and the pizza enthusiasts at your table. If you enjoy this fusion dish, you might also love trying a Crispy Pepperoni Lasagna that combines the flavors of pepperoni pizza with traditional lasagna layers.
Make it for busy school nights, casual weekend gatherings, or anytime you need a reliable crowd-pleaser.
There’s something undeniably satisfying about watching cheese pull into long, stretchy strands as you scoop up each hearty, comforting bite.